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Title:
CYCLOPENTANE DERIVATIVE
Document Type and Number:
Japanese Patent JP3169144
Kind Code:
B2
Abstract:

PURPOSE: To obtain a new compound capable of exhibiting a thymulin-like activity and useful as a therapeutic agent, etc., for immunodeficiency and autoimmune diseases, etc.
CONSTITUTION: A compound of formula I [R1 and R2 are (protected)hydroxy or (protected)sulfhydryl; X is carboxyl, lower-alkoxycarbonyl, =O, etc.; A and B are each lower alkylene], e.g. c-2,c-4-bis(benzylthiomethyl)-γ-1- cyclopentanecarboxylic acid. Furthermore, the compound of formula I is obtained by treating e.g. a compound of formula II in a liquid ammonia in the presence of metallic sodium.


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Inventors:
Shiro Mita
Youichi Kawashima
Morishita Masataka
Application Number:
JP7894392A
Publication Date:
May 21, 2001
Filing Date:
February 28, 1992
Export Citation:
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Assignee:
Santen Pharmaceutical Co., Ltd.
International Classes:
A61K31/075; A61K31/095; A61K31/12; A61K31/122; A61K31/19; A61K31/215; A61K31/357; A61P37/00; A61P37/04; A61P43/00; C07C31/135; C07C43/30; C07C49/493; C07C62/02; C07C62/08; C07C69/757; C07C323/22; C07C323/53; (IPC1-7): C07C49/493; A61K31/075; A61P37/04; A61P43/00; C07C62/02; C07C69/757; C07C323/22
Domestic Patent References:
JP5213961A
Other References:
【文献】国際公開92/12129(WO,A1)
Attorney, Agent or Firm:
Toshiharu Nakatsuji



 
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