Title:
上皮-間葉移行に関与するサイトカイン
Document Type and Number:
Japanese Patent JP4851327
Kind Code:
B2
Abstract:
The functional characterization of ILEI to be a novel cytokine involved in epithelial/mesenchymal transition and the identification of biologically active ILEI provides the basis for generating ILEI inhibitors, in particular anti-ILEI antibodies, that are useful in the therapy of cancer, fibrosis and COPD.
Inventors:
Werner Thomas
Boyk Hartmut
Jechlinger Martin
Grunert Stefan
Tamil Edo
Kraut Norbert
Heider Karl Heinz
Zeiter Peter
Weit Andreas
Zeffel Andreas
Konopitsky Renate
Horn holst
Jung Bilgit
Boyk Hartmut
Jechlinger Martin
Grunert Stefan
Tamil Edo
Kraut Norbert
Heider Karl Heinz
Zeiter Peter
Weit Andreas
Zeffel Andreas
Konopitsky Renate
Horn holst
Jung Bilgit
Application Number:
JP2006525104A
Publication Date:
January 11, 2012
Filing Date:
September 02, 2004
Export Citation:
Assignee:
Boehringer Ingelheim International GmbH
International Classes:
A61K39/395; A61P17/02; A61P35/00; A61P35/04; C07K14/52; C07K16/24; C12N15/09; C12N15/113; C12N15/19; A61K38/00
Foreign References:
| WO2002063009A2 | 2002-08-15 | |||
| US6506607B1 | 2003-01-14 |
Attorney, Agent or Firm:
Sadao Kumakura
Atsushi Hakoda
Kenji Asai
Toshio Takizawa
Atsushi Hakoda
Kenji Asai
Toshio Takizawa