Title:
細胞障害性ベンゾジアゼピン誘導体
Document Type and Number:
Japanese Patent JP7132311
Kind Code:
B2
Abstract:
The invention relates to novel benzodiazepine derivatives with antiproliferative activity and more specifically to novel benzodiazepine compounds of formula (I)-(VI). The invention also provides conjugates of the benzodiazepine compounds linked to a cell-binding agent. The invention further provides compositions and methods useful for inhibiting abnormal cell growth or treating a proliferative disorder in a mammal using the compounds or conjugates of the invention.
Inventors:
Chari, Ravi V. Jay
Miller, Michael Lewis
Shizuka, Manami
Miller, Michael Lewis
Shizuka, Manami
Application Number:
JP2020195666A
Publication Date:
September 06, 2022
Filing Date:
November 26, 2020
Export Citation:
Assignee:
Immunogen Incorporated
International Classes:
C07D519/00; C07K5/06; C07K5/08; C07K5/10; C07K7/04; C07K16/28
Domestic Patent References:
| JP6606545B2 |
Attorney, Agent or Firm:
Osamu Yamamoto
Toru Miyamae
Toru Miyamae