Title:
DNA-PK阻害剤
Document Type and Number:
Japanese Patent JP2008535903
Kind Code:
A
Abstract:
Compounds of formula I: wherein A, B and D are respectively selected from the group consisting of: (i) CH, NH, C; (ii) CH, N, N; and (iii) CH, O, C; the dotted lines represent two double bonds in the appropriate locations; and where Z is selected from S, O, C(═O), CH2 and NH are disclosed for use in inhibiting DNA-PK.
Inventors:
Smith, Graeme Cameron Murray
Martin, Neil Morrison Bar
Cockcroft, Xiao-Ling Fan
Minnea, Keith Alan
Hummerson, mark jeffrey
Griffin, Roger John
Friggerio, mark
Golding, Bernard Thomas
Hard Castle, Ian Robert
Newell, David, Richard
Culvert, Hillary Alan
Curtin, Nikola Jane
Dessage-El Meur, Marin
Martin, Neil Morrison Bar
Cockcroft, Xiao-Ling Fan
Minnea, Keith Alan
Hummerson, mark jeffrey
Griffin, Roger John
Friggerio, mark
Golding, Bernard Thomas
Hard Castle, Ian Robert
Newell, David, Richard
Culvert, Hillary Alan
Curtin, Nikola Jane
Dessage-El Meur, Marin
Application Number:
JP2008505966A
Publication Date:
September 04, 2008
Filing Date:
April 13, 2006
Export Citation:
Assignee:
Kudos Pharmaceuticals Limited
International Classes:
C07D215/38; A61K31/5377; A61P31/14; A61P35/00; A61P43/00; C07D311/58; C07D405/04; C07D405/12; C07D405/14; C07D407/12; C07D409/04; C07D409/10; C07D409/14; C07D413/12; C07D417/04; C07D417/10; C07D417/14; C07D471/04; C12N9/99
Domestic Patent References:
| JP2003530318A | 2003-10-14 | |||
| JP2005503414A | 2005-02-03 |
Attorney, Agent or Firm:
Yusuke Hiraki
Ishii Teiji
Satoshi Fujita
Ishii Teiji
Satoshi Fujita