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Title:
DNA-PK inhibitor
Document Type and Number:
Japanese Patent JP6360878
Kind Code:
B2
Abstract:
The present invention relates to compounds useful as inhibitors of DNA-PK. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.

Inventors:
Maxwell, John Patrick
Charifson, Paul S.
Tan, Chin
Ronkin, Stephen M.
Jackson, Katrina Lee
Pearce, Albert Charles
Lauffer, David Jay.
Lee bread
Girou, Simon
Shu, Jin Wan
Cottrell, Kevin M.
Morris, Mark A.
Whirl, Nathan Dee.
Court, John Jay.
Gu, Wen Shin
Den, hombo
Application Number:
JP2016501636A
Publication Date:
July 18, 2018
Filing Date:
March 12, 2014
Export Citation:
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Assignee:
VERTEX PHARMACEUTICALS INCORPORATED
International Classes:
C07D241/42; A61K31/506; A61K31/5377; A61K31/5386; A61P35/00; A61P43/00; C07D271/12; C07D401/12; C07D401/14; C07D403/12; C07D403/14; C07D405/12; C07D405/14; C07D413/12; C07D413/14; C07D417/12; C07D471/04; C07D473/34; C07D475/00; C07D487/04; C07D491/048; C07D491/052; C07D491/056; C07D498/04; C07D498/08; C07D513/04
Domestic Patent References:
JP2011246389A
Foreign References:
WO2002020500A2
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita