ｖＷＦに結合するＤＮＡアプタマー

Title:

ｖＷＦに結合するＤＮＡアプタマー

Document Type and Number:

Japanese Patent JP6721189

Kind Code:

B2

Abstract:

The purpose of the present invention is to provide an aptamer for vWF, which is superior in a binding ability, a dissociation rate, and/or stability to the conventional nucleic acid aptamers. The present invention can solve the problem by a DNA aptamer which contains artificial nucleotides and binds to vWF.

More Like This:

JP6619211	Aptamer that binds to the cell nucleus transport receptor KPNA2 protein, and functional inhibition of KPNA2 protein using it
JP2023545229	Nucleic acids encoding anti-VEGF entities and negative complement regulators and their use for the treatment of age-related macular degeneration
JP2023527555	Compositions and methods for enhancing visual function

Inventors:

Ichiro Hirao
Michiko Hirao
Kenichiro Matsunaga

Application Number:

JP2017547793A

Publication Date:

July 08, 2020

Filing Date:

October 25, 2016

Export Citation:

Click for automatic bibliography generation Help

Assignee:

Tag Six Bio Inc.

International Classes:

C12N15/115; A61K31/7088; A61K48/00; A61P7/02; A61P9/08; A61P9/10; C12Q1/6806; G01N33/53

Domestic Patent References:

JP2008512098A

Foreign References:

WO2010091396A1
US20090203766
WO2013073602A1

Other References:

Structure,2009年,Vol.17, No.11,pp.1476-1484
Nature Biotechnology,2013年,Vol.31, No.5,pp.453-457

Attorney, Agent or Firm:

Hiraki International Patent Office

Previous Patent: プランジャアセンブリ

Next Patent: 通信システム