Title:
癌細胞に結合するＤＮＡアプタマー
Document Type and Number:
Japanese Patent JP7041517
Kind Code:
B2
Abstract:
The purpose of the present invention is to provide an aptamer to a cancer cell, said aptamer being superior to conventional aptamers in binding ability, specificity, and/or stability. To solve this problem, provided is a DNA aptamer binding to a cancer cell, said DNA aptamer containing an artificial base(s).
Inventors:
Kazunobu Futami
Ichiro Hirao
Michiko Hirao
Ichiro Hirao
Michiko Hirao
Application Number:
JP2017547792A
Publication Date:
March 24, 2022
Filing Date:
October 25, 2016
Export Citation:
Assignee:
Agency for Science, Technology and Research
International Classes:
C12N15/115; A61K31/711; A61K45/00; A61K47/59; A61K48/00; A61P15/00; A61P35/00; A61P43/00; C12Q1/6886
Domestic Patent References:
| JP2015513919A |
Foreign References:
| WO2014191359A1 | ||||
| US20110166213 | ||||
| WO2013073602A1 |
Other References:
Analytical Chemistry,2014年,Vol.86, No.13,pp.6596-6603
Nature Biotechnology,2013年,Vol.31, No.5,pp.453-457
Nature Biotechnology,2013年,Vol.31, No.5,pp.453-457
Attorney, Agent or Firm:
Takashima Hajime
Mitsuyoshi Kamada
Kyoko Doi
Yaeko Tamura
Hirofumi Taima
Atsuko Akai
Tomiya Tosaki
Mitsuyoshi Kamada
Kyoko Doi
Yaeko Tamura
Hirofumi Taima
Atsuko Akai
Tomiya Tosaki