Title:
ヒト血管形成遺伝子に対するDNA配列
Document Type and Number:
Japanese Patent JP4486815
Kind Code:
B2
Abstract:
Novel nucleic acid sequences and encoded polypeptides involved in the process of angiogenesis are provided. In particular, provided are a BNO69 nucleic acid of SEQ ID NO: 1 and a BNO69 polypeptide of SEQ ID NO: 115. Methods are provided for treating subjects having pathologies associated with angiogenesis and for the screening of drugs for pro- or anti-angiogenic activity.
Inventors:
Gumble, jennifer, luth
Hahn, christopher, norman
Vadas, Matthew, Alexander
Hahn, christopher, norman
Vadas, Matthew, Alexander
Application Number:
JP2003530854A
Publication Date:
June 23, 2010
Filing Date:
September 19, 2002
Export Citation:
Assignee:
Bionomics limited
International Classes:
A01K67/027; C12N15/09; A61K45/00; A61P3/10; A61P9/00; A61P9/10; A61P17/06; A61P19/02; A61P27/02; A61P29/00; A61P35/00; C07K14/47; C07K16/18; C12N1/15; C12N1/19; C12N5/10; C12N15/113; C12P21/02; C12P21/08; C12Q1/02; C12Q1/68; G01N33/15; G01N33/50; G01N33/53; G01N33/566; A61K38/00
Foreign References:
| WO2001012659A1 | ||||
| WO2001032926A1 |
Other References:
Biochem Biophys Res Commun. ,2000年 3月,Vol.269, No.2,p.633-640
The suppression of small GTPase rho signal transduction pathway inhibits angiogenesis in vitro and in vivo.,Biochem Biophys Res Commun. ,The suppression of small GTPase rho signal transduction pathway inhibits angiogenesis in vitro and in vivo.,2000年 3月,Vol.269, No.2,p.633-640
The suppression of small GTPase rho signal transduction pathway inhibits angiogenesis in vitro and in vivo.,Biochem Biophys Res Commun. ,The suppression of small GTPase rho signal transduction pathway inhibits angiogenesis in vitro and in vivo.,2000年 3月,Vol.269, No.2,p.633-640
Attorney, Agent or Firm:
Nobuaki Kazehaya
Noriko Asano
Noriko Asano