Title:
DAMAGED WOUND HEALING COMPOSITION AND THERAPY
Document Type and Number:
Japanese Patent JP2014144976
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide a damaged wound healing composition and therapy.SOLUTION: A method and composition comprising a combination and use of a first anti-connexin agent and a second anti-connexin agent, for example, one or more anti-connexin polynucleotide and one or more anti-connexin peptide or anti-connexin peptidomimetic agent are provided for therapeutic use comprising use for facilitation and/or improvement in wound and wound healing and/or tissue repairing. The present invention encompasses a pharmaceutical composition comprising (a) an anti-connexin peptide or an anti-connexin peptidomimetic agent and (b) a polynucleotide of an antisense to mRNA of connexin protein.
Inventors:
DUFT BRADFORD J
Application Number:
JP2014097425A
Publication Date:
August 14, 2014
Filing Date:
May 09, 2014
Export Citation:
Assignee:
CODA THERAPEUTICS INC
International Classes:
A61K38/00; A61K9/06; A61K9/70; A61K31/7088; A61K39/395; A61K47/34; A61K47/38; A61K48/00; A61L15/44; A61P3/10; A61P9/00; A61P43/00; C12N15/113; A61P17/02
Domestic Patent References:
| JP2002535377A | 2002-10-22 |
Foreign References:
| WO2006134494A2 | 2006-12-21 |
Other References:
JPN7013002160; Ｊｏｕｒｎａｌ ｏｆ Ｃｅｌｌ Ｓｃｉｅｎｃｅ Ｖｏｌ．１１９, 2006, ｐ．５１９３-５２０３
JPN7013002161; Ｄｉａｂｅｔｅｓ Ｖｏｌ．５６, 200711, ｐ．２８０９-２８１７
JPN7013002162; Ａｎｎａｌｓ ｏｆ ｔｈｅ Ｎｅｗ Ｙｏｒｋ Ａｃａｄｅｍｙ ｏｆ Ｓｃｉｅｎｃｅｓ Ｖｏｌ．１０８０, 2006, ｐ．４９-６２
JPN7013002163; Ｊｏｕｒｎａｌ ｏｆ Ｉｎｖｅｓｔｉｇａｔｉｖｅ Ｄｅｒｍａｔｏｌｏｇｙ Ｖｏｌ．１２８, 200710, ｐ．１０３９-１０４９
JPN7013002161; Ｄｉａｂｅｔｅｓ Ｖｏｌ．５６, 200711, ｐ．２８０９-２８１７
JPN7013002162; Ａｎｎａｌｓ ｏｆ ｔｈｅ Ｎｅｗ Ｙｏｒｋ Ａｃａｄｅｍｙ ｏｆ Ｓｃｉｅｎｃｅｓ Ｖｏｌ．１０８０, 2006, ｐ．４９-６２
JPN7013002163; Ｊｏｕｒｎａｌ ｏｆ Ｉｎｖｅｓｔｉｇａｔｉｖｅ Ｄｅｒｍａｔｏｌｏｇｙ Ｖｏｌ．１２８, 200710, ｐ．１０３９-１０４９
Attorney, Agent or Firm:
Shusaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto