Title:
DAMAVARICIN FC DERIVATIVE
Document Type and Number:
Japanese Patent JPS643190
Kind Code:
A
Abstract:
NEW MATERIAL:A compound expressed by formula I [A is expressed by formula II (B is methylene, O or S; l is 0 or 1; m and n are 0W6; R1 and R2 are methyl or ethyl; R3 is 1W5C alkyl; R4 is H, methyl or ethyl)].
EXAMPLE: 19-O-Trimethylsilylmethyldamavaricin Fc.
USE: An antimicrobial and antiviral agent having low acute toxicity and high intracorporeal absorbability.
PREPARATION: For example, a halide expressed by formula III (X is halogen, such as Cl, Br or I) is reacted with damavaricin Fc in the presence of silver ions, such as silver oxide, in a solvent, such as methanol, at 0W80°C.
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Inventors:
YAGIHASHI FUJIO
YAMAMOTO AKIRA
MOTOMIYA TATSUHIKO
YAMAMOTO AKIRA
MOTOMIYA TATSUHIKO
Application Number:
JP15856087A
Publication Date:
January 06, 1989
Filing Date:
June 25, 1987
Export Citation:
Assignee:
SHINETSU CHEMICAL CO
International Classes:
A01N55/00; A61K31/695; A61P31/04; A61P31/12; C07F7/10; (IPC1-7): A01N55/00; A61K31/695; C07F7/10
Attorney, Agent or Firm:
Shuji Iwamiya
Next Patent: PRODUCTION OF ORGANOGERMANIUM COMPOUND