DEAZAPURINE USEFUL AS INHIBITOR OF JANUS KINASE

Title:

DEAZAPURINE USEFUL AS INHIBITOR OF JANUS KINASE

Document Type and Number:

Japanese Patent JP2014024869

Kind Code:

A

Abstract:

To provide compounds useful as inhibitors of protein kinases.

The present invention relates to compounds useful as inhibitors of protein kinases, particularly of JAK family kinases. The invention also provides pharmaceutically acceptable compositions comprising the compounds and methods of using the compositions in the treatment of various diseases, conditions, or disorders. These compounds, and pharmaceutically acceptable compositions thereof, are useful for treating or lessening the severity of a variety of disorders, including proliferative disorders, cardiac disorders, neurodegenerative disorders, autoimmune disorders, conditions associated with organ transplantation, inflammatory disorders, or immunologically mediated disorders in a patient.

More Like This:

JP2022507697	Compounds and compositions for treating conditions associated with STING activity
JP2004352685	COMPOSITION CONTAINING PYRAZOLE COMPOUND FOR PROMOTING ACCUMULATION AND/OR SUPPRESSING DECREASE IN COLLAGEN
JP2968002	INDUSTRIAL APPLICABILITY: Novel 2'-halomethylidene, 2'-ethenylidene and 2'-ethynyl adenosine derivatives

Inventors:

LEDEBOER MARK
MESSERSMITH DAVID
MALTAIS FRANCOIS
GAO HUAI
WANG TIANSHENG
CAO JINGRONG
DUFFY JOHN
MARTINEZ-BOTELLA GABRIEL
FORSTER CORNELIA
MARONE VALERIE
WANNAMAKER MARION
SALITURO FRANCESCO
PIERCE ALBERT
FARMER LUC

Application Number:

JP2013228595A

Publication Date:

February 06, 2014

Filing Date:

November 01, 2013

Export Citation:

Click for automatic bibliography generation Help

Assignee:

VERTEX PHARMA

International Classes:

C07D487/04; A61K31/519; A61K45/00; A61P3/10; A61P9/00; A61P11/06; A61P17/06; A61P17/14; A61P19/02; A61P21/00; A61P25/00; A61P25/14; A61P25/16; A61P25/18; A61P25/28; A61P29/00; A61P31/18; A61P35/00; A61P35/02; A61P37/06; A61P37/08; A61P43/00

Domestic Patent References:

JP2002518394A	2002-06-25
JP2003518123A	2003-06-03

Foreign References:

WO2005068468A2	2005-07-28
WO2004072063A1	2004-08-26
WO2007070514A1	2007-06-21

Attorney, Agent or Firm:

Hidesaku Yamamoto
Natsuki Morishita

Previous Patent: モールドの製造方法、および微細凹凸構造を表面に有する成形体の製造方�...

Next Patent: CATHETER LOCK SOLUTION HAVING BACTERIOSTATIC EFFECT AND PROCESS FOR PREPARING THE CATHETER LOCK SOLU...