Title:
所定の吸入ルートによる鎮静睡眠剤の送出
Document Type and Number:
Japanese Patent JP4578772
Kind Code:
B2
Abstract:
The present invention relates to the delivery of antipsychotics through an inhalation route. Specifically, it relates to aerosols containing antipsychotics that are used in inhalation therapy. In a composition aspect of the present invention, the aerosol comprises particles comprising at least 5 percent by weight of an antipsychotic. In a method aspect of the present invention, an antipsychotic is delivered to a mammal through an inhalation route. The method comprises: a) Heating a composition, wherein the composition comprises at least 5 percent by weight of an antipsychotic, to form a vapor; and, b) allowing the vapor to cool, thereby forming a condensation aerosol comprising particles, which is inhaled by the mammal. In a kit aspect of the present invention, a kit for delivering an antipsychotic through an inhalation route to a mammal is provided which comprises: a) a composition comprising at least 5 percent by weight of an antipsychotic; and, b) a device that forms an antipsychotic containing aerosol from the composition, for inhalation by the mammal.
Inventors:
Rabinowits Joshua, Dee.
Zafaroni, Alegend Rocy.
Zafaroni, Alegend Rocy.
Application Number:
JP2002590949A
Publication Date:
November 10, 2010
Filing Date:
May 17, 2002
Export Citation:
Assignee:
Alec The Pharmaceuticals, Incorporated
International Classes:
A61K9/12; A61K31/437; A61K9/00; A61K9/72; A61K31/00; A61K31/13; A61K31/137; A61K31/138; A61K31/165; A61K31/167; A61K31/19; A61K31/192; A61K31/216; A61K31/27; A61K31/40; A61K31/403; A61K31/404; A61K31/4045; A61K31/405; A61K31/407; A61K31/4196; A61K31/421; A61K31/422; A61K31/423; A61K31/439; A61K31/4402; A61K31/4418; A61K31/4525; A61K31/4545; A61K31/46; A61K31/473; A61K31/48; A61K31/485; A61K31/49; A61K31/495; A61K31/496; A61K31/4985; A61K31/501; A61K31/505; A61K31/519; A61K31/53; A61K31/5415; A61K31/55; A61K31/551; A61K31/5513; A61K31/5517; A61K45/00; A61K47/48; A61M11/00; A61P15/10; A61P21/02; A61P25/06; A61P25/08; A61P25/16; A61P25/18; A61P25/20; A61P25/22; A61P25/24; A61P25/32; A61P29/00; A61P31/04; A61P37/08; A61P43/00; C07D471/04; C07D487/04; F24V30/00
Foreign References:
| WO1997040819A1 | ||||
| WO2000015262A1 | ||||
| WO2001013895A1 | ||||
| WO2000050007A1 |
Other References:
橋爪 祐二,日本臨床,1998年,第56巻,第2号,p.240-244
横地 明,1 各種吸入用粒子発生法とその特徴,NIRS-M(National Inst. of Radiologial Sciences,1991年,p.3-12
横地 明,1 各種吸入用粒子発生法とその特徴,NIRS-M(National Inst. of Radiologial Sciences,1991年,p.3-12
Attorney, Agent or Firm:
Shinjiro Ono
Kazuo Shamoto
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Hiroko Ejiri
Kazuo Shamoto
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Hiroko Ejiri