Title:
DERIVATIVE OF RIFAMYCIN S AND SV
Document Type and Number:
Japanese Patent JPS54117497
Kind Code:
A
Abstract:
8-amino and 8-iminorifamycins S and SV are prepared by reacting 8-methoxyrifamycin S with ammonia in an inert polar and hydrophillic solvent, converting the 8-iminorifamycin S into 8 aminorifamycin S by reaction with ammonium hydroxide in a mixture of chloroform and methanol and, if so desired, reducing the S forms to SV forms by reduction.
Inventors:
EGIDEIO MARUKI
RAURETSUTA MONTETSUKI
RAURETSUTA MONTETSUKI
Application Number:
JP15729778A
Publication Date:
September 12, 1979
Filing Date:
December 20, 1978
Export Citation:
Assignee:
ALFA FARMACEUTICI SPA
International Classes:
A61K31/395; A61P31/04; C07D498/08; (IPC1-7): A61K31/395; C07D498/08
Previous Patent: JPS54117496
Next Patent: 1*11DISUBSTITUTED OCTAHYDROOINDOLO*2*33A* QUINOLIDINE*ITS MANUFACTURE AND COMPOSITION CONTAINING IT
Next Patent: 1*11DISUBSTITUTED OCTAHYDROOINDOLO*2*33A* QUINOLIDINE*ITS MANUFACTURE AND COMPOSITION CONTAINING IT