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Patent Searching and Data


Title:
ヒト第VIII因子の少なくとも1ドメインと相互作用するスタフィロコッカスタンパク質A(SPA)由来のBまたはZドメインの誘導体
Document Type and Number:
Japanese Patent JP4578690
Kind Code:
B2
Abstract:
The present invention relates to modified polypeptides which are derivatives of the B domain or Z domain from staphylococcal protein A (SPA), wherein between 1 and 20 amino acid residues of the said B or Z domain have been substituted by other amino acid residues, said substitution being made without substantial loss of the basic structure and stability of the said B or Z domain, and said substitution resulting in interaction capacity of the said polypeptide with at least one domain of human Factor VIII protein.

Inventors:
Charlotte Jungkwist
Karin Node
Pale-Ok Negren
Matthias Woolen
Application Number:
JP2000612330A
Publication Date:
November 10, 2010
Filing Date:
April 17, 2000
Export Citation:
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Assignee:
Biovitrum AB(publ)
International Classes:
C07K14/195; C12P21/02; C07K1/22; C07K14/31; C12N15/10
Domestic Patent References:
JP9508016A
Attorney, Agent or Firm:
Aoyama Aoi
Mitsutaka Iwasaki