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Title:
【発明の名称】RANK発現のアンチセンスモジュレーション
Document Type and Number:
Japanese Patent JP2003513650
Kind Code:
A
Abstract:
Antisense compounds, compositions and methods are provided for inhibiting the expression of RANK. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding RANK. Methods of using these compounds for inhibition of RANK expression and for treatment of diseases associated with expression of RANK are provided.

Inventors:
Baker, Brenda F
Kausart, Rex M
Application Number:
JP2001536753A
Publication Date:
April 15, 2003
Filing Date:
October 30, 2000
Export Citation:
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Assignee:
Isis PharmaceuticalsInc
International Classes:
C12N15/09; A61K9/10; A61K31/7125; A61K48/00; A61P19/00; A61P19/10; A61P29/00; A61P35/00; A61P43/00; C07H21/04; C12N15/113; C12Q1/68; A61K38/00; (IPC1-7): C12N15/09; A61K9/10; A61K31/7125; A61K48/00; A61P19/00; A61P19/10; A61P29/00; A61P35/00; A61P43/00; C07H21/04; C12Q1/68
Attorney, Agent or Firm:
Kazuo Shamoto (5 outside)