【発明の名称】乳酸アシドーシスによる不可逆的損傷から細胞及び組織を保護する化合物及び方法 - The Regents of The University of California

Title:

【発明の名称】乳酸アシドーシスによる不可逆的損傷から細胞及び組織を保護する化合物及び方法

Document Type and Number:

Japanese Patent JPH06505484

Kind Code:

A

Abstract:

Compounds and a method useful for protection of tissue cells in a mammalian body from irreversible damages due to lactic acidosis caused by oxygen deficiency. The protection is achieved by administering a compound having a cell membrane permeability and/or ability to cross the blood brain barrier and being able to provide a buffering action to prevent an increase in a hydrogen ion concentration over the physiologically acceptable levels.

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Inventors:

Nakada, Tutom

Application Number:

JP50742892A

Publication Date:

June 23, 1994

Filing Date:

March 05, 1992

Export Citation:

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Assignee:

The Regents of The University of California

International Classes:

A61K31/185; A61K31/19; A61K31/495; A61K31/5375; A61P3/00; A61P9/00; C07C211/00; C07C229/00; C07C233/02; C07C239/08; C07C271/00; C07C275/00; C07C279/00; C07C309/14; C07C309/16; (IPC1-7): C07C211/00; A61K31/185; A61K31/19; C07C229/00; C07C233/02; C07C239/08; C07C271/00; C07C275/00; C07C279/00; C07C309/14; C07C309/16

Attorney, Agent or Firm:

Atsushi Nakajima (2 outside)

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