【発明の名称】抗原提示細胞におけるエピトープ同調

Japanese Patent JP2003535824

A

Disclosed herein are vaccines and methods for inducing an immune response against cancer cells and cells infected with intracellular parasites. Vaccines having housekeeping epitopes are disclosed. The housekeeping epitope is formed by housekeeping proteasomes in peripheral cells, but not by professional antigen presenting cells. A vaccine containing a housekeeping epitope that is derived from an antigen associated with a peripheral target cell can thus direct an immune response against the target cell. Methods of treatment are also disclosed, which involve administering a vaccine having a housekeeping epitope.

JPH06303984	RECOMBINANT DNA, YEAST TRANSFORMED THEREWITH AND PRODUCTION OF AQUALYSIN I USING THE SAME
WO/1998/008957	COMPOSITIONS AND METHODS FOR SPECIFICALLY TARGETING TUMORS
WO/2002/046437	METHODS AND COMPOSITIONS FOR HIGHLY EFFICIENT PRODUCTION OF HETEROLOGOUS PROTEINS IN YEAST

Shimmered, John Jay Elle.
Diamond, David Sea.
Lee, Cyan-Don

JP2001579836A

December 02, 2003

April 27, 2001

Click for automatic bibliography generation  

CT L Immunotherapy Corporation

C12N15/09; A61K39/00; A61K39/002; A61K39/008; A61K39/015; A61K39/02; A61K39/04; A61K39/10; A61K39/112; A61K39/118; A61K39/12; A61K39/13; A61K39/20; A61K39/21; A61K39/23; A61K39/235; A61K39/245; A61K39/29; A61P31/00; A61P35/00; C07K16/18; C12N5/10; C12Q1/68; (IPC1-7): A61K39/12; A61K39/00; A61K39/002; A61K39/008; A61K39/015; A61K39/02; A61K39/04; A61K39/10; A61K39/112; A61K39/118; A61K39/13; A61K39/20; A61K39/21; A61K39/23; A61K39/235; A61K39/245; A61K39/29; A61P35/00; C07K16/18; C12N5/10; C12N15/09; C12Q1/68

WO1997041440A1

1997-11-06

Tsutomu Toyama (3 others)

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