Title:
【発明の名称】抗腫瘍剤の毒性を低減するための調合物及び方法
Document Type and Number:
Japanese Patent JP2001520189
Kind Code:
A
Abstract:
This invention provides for pharmaceutical formulations of compounds which are useful as protective agents when administered to patients also receiving antineoplastic drugs. The invention also includes methods of reducing the toxicity of various antineoplastic agents by administering an effective amount of the protective agent to a patient receiving one or more antineoplastic agents. The compounds useful as protective agents have either a sulfhydryl moiety or are reducible disulfides.
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Inventors:
Hausher, frederick, h
Dodd, Thomas, Jay
Dodd, Thomas, Jay
Application Number:
JP2000516661A
Publication Date:
October 30, 2001
Filing Date:
October 16, 1998
Export Citation:
Assignee:
Bionumeric Pharmaceuticals Incorporated
International Classes:
A61K31/02; A61K31/131; A61K31/136; A61K31/166; A61K31/175; A61K31/185; A61K31/196; A61K31/198; A61K31/255; A61K31/28; A61K31/282; A61K31/337; A61K31/36; A61K31/40; A61K31/407; A61K31/4164; A61K31/439; A61K31/44; A61K31/4745; A61K31/495; A61K31/505; A61K31/506; A61K31/513; A61K31/517; A61K31/519; A61K31/52; A61K31/522; A61K31/53; A61K31/662; A61K31/675; A61K31/7008; A61K31/704; A61K31/7048; A61K31/7056; A61K31/7068; A61K31/7076; A61K33/243; A61K45/06; A61P35/00; A61P39/02; A61P43/00; (IPC1-7): A61K31/185; A61K31/02; A61K31/131; A61K31/136; A61K31/166; A61K31/175; A61K31/196; A61K31/198; A61K31/255; A61K31/282; A61K31/337; A61K31/36; A61K31/407; A61K31/4164; A61K31/439; A61K31/44; A61K31/4745; A61K31/495; A61K31/505; A61K31/506; A61K31/513; A61K31/517; A61K31/519; A61K31/52; A61K31/522; A61K31/53; A61K31/662; A61K31/675; A61K31/7008; A61K31/704; A61K31/7048; A61K31/7056; A61K31/7068; A61K31/7076; A61K33/24; A61K45/06; A61P35/00; A61P39/02; A61P43/00
Attorney, Agent or Firm:
Sakai Hajime