Title:
【発明の名称】免疫調節のための方法および組成物
Document Type and Number:
Japanese Patent JP2003527400
Kind Code:
A
Abstract:
Methods and compositions for inducing immune suppression are disclosed. The methods involve administering an effective amount of an agent that inhibits MD-1 with or without an OX-2 protein or a nucleic acid encoding an OX-2 protein. The methods are useful in preventing graft rejection, fetal loss, autoimmune disease, and allergies. Methods and compositions for preventing immune suppression are also disclosed. The methods involve administering an effective amount of MD-1 or an agent that activates or stimulates MD-1.
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Inventors:
Gotsynski Reginald M.
Clark David A.
Clark David A.
Application Number:
JP2001567787A
Publication Date:
September 16, 2003
Filing Date:
March 16, 2001
Export Citation:
Assignee:
Transplantation Technologies, Inc.
International Classes:
G01N33/50; A61K31/7088; A61K38/00; A61K39/395; A61K45/00; A61K48/00; A61P1/00; A61P1/04; A61P1/16; A61P3/10; A61P5/14; A61P7/00; A61P7/02; A61P7/06; A61P9/00; A61P11/00; A61P13/12; A61P15/06; A61P17/00; A61P17/02; A61P17/06; A61P19/02; A61P21/00; A61P21/04; A61P25/00; A61P25/28; A61P27/00; A61P29/00; A61P31/00; A61P31/04; A61P35/00; A61P37/02; A61P37/04; A61P37/06; A61P37/08; A61P43/00; C07K16/18; C07K16/28; C12N15/09; C12N15/113; G01N33/15; (IPC1-7): A61K45/00; A61K31/7088; A61K38/00; A61K39/395; A61K48/00; A61P1/00; A61P1/04; A61P1/16; A61P3/10; A61P5/14; A61P7/00; A61P7/02; A61P7/06; A61P9/00; A61P11/00; A61P13/12; A61P15/06; A61P17/00; A61P17/02; A61P17/06; A61P19/02; A61P21/00; A61P21/04; A61P25/00; A61P25/28; A61P27/00; A61P29/00; A61P31/00; A61P31/04; A61P35/00; A61P37/02; A61P37/04; A61P37/06; A61P37/08; A61P43/00; C12N15/09; G01N33/15; G01N33/50
Attorney, Agent or Firm:
Shimizu Hatsushi (1 person outside)