Title:
【発明の名称】新規なイソオキサゾリンおよびイソオキサゾールフィブリノーゲン受容体拮抗薬
Document Type and Number:
Japanese Patent JPH11504651
Kind Code:
A
Abstract:
This invention relates to novel isoxazolines and isoxazoles which are useful as antagonists of the platelet glycoprotein IIb/IIIa fibrinogen receptor complex or the vitronectin receptor, to pharmaceutical compositions containing such compounds, processes for preparing such compounds, and to methods of using these compounds, alone or in combination with other therapeutic agents, for the inhibition of platelet aggregation, as thrombolytics, and/or for the treatment of thromboembolic disorders.
Inventors:
Vit Yak, Jiyoung
Kane, Gary Avon
Butt, Douglas Guy
Pintow, Donald
Hussein, Mounia Alwan
Shiyu, Chiyu-Biao
Sieleky-Jyurz, Tyce Motorria
Allson, Littleyard Erick
Degradado, William Frank
Mosa, Shaker Ahmed
Kane, Gary Avon
Butt, Douglas Guy
Pintow, Donald
Hussein, Mounia Alwan
Shiyu, Chiyu-Biao
Sieleky-Jyurz, Tyce Motorria
Allson, Littleyard Erick
Degradado, William Frank
Mosa, Shaker Ahmed
Application Number:
JP53657996A
Publication Date:
April 27, 1999
Filing Date:
May 30, 1996
Export Citation:
Assignee:
The DuPont Merck Pharmaceuticals Company
International Classes:
A61K31/42; A61K31/423; A61K31/425; A61K31/435; A61K31/44; A61K31/445; A61K31/47; A61K31/495; A61K31/496; A61K31/50; A61K31/505; A61K31/535; A61K31/5377; A61K31/55; A61K31/66; A61K31/665; A61K45/00; A61P1/00; A61P3/08; A61P3/10; A61P7/02; A61P7/04; A61P9/08; A61P9/10; A61P11/00; A61P17/00; A61P19/10; A61P27/02; A61P27/14; A61P29/00; A61P31/04; A61P35/00; A61P37/00; A61P37/08; A61P43/00; C07D261/04; C07D261/06; C07D261/10; C07D261/12; C07D261/18; C07D261/20; C07D413/04; C07D413/06; C07D413/12; C07D413/14; C07D417/12; C07D498/10; C07F7/10; C07F9/653; C07F9/6571; (IPC1-7): C07D261/18; A61K31/42; A61K31/435; A61K31/445; A61K31/495; A61K31/535; A61K31/55; A61K45/00; C07D261/10; C07D261/12; C07D261/20; C07D413/12; C07D498/10
Attorney, Agent or Firm:
Chika Takagi (2 outside)