Title:
【発明の名称】乳房の疾患の検出に有用な試薬および方法
Document Type and Number:
Japanese Patent JP2001521744
Kind Code:
A
Abstract:
A set of contiguous and partially overlapping RNA sequences and polypeptides encoded thereby, designated as BS106 and transcribed from breast tissue is described. These sequences are useful for the detecting, diagnosing, staging, monitoring, prognosticating, preventing or treating, or determining the predisposition of an individual to diseases and conditions of the breast such as breast cancer. Also provided are antibodies which specifically bind to BS106-encoded polypeptide or protein, and agonists or inhibitors which prevent action of the tissue-specific BS106 polypeptide, which molecules are useful for the therapeutic treatment of breast diseases, tumors or metastases.
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Inventors:
Billings-Medel, Patricia A
Cohen, Maurice
Colpitts, Tracy El
Friedman, Paula N
Gordon, The Julian
Edward, Granados
Hotisu, Stephen Sea
Class, michael are
Kratokville, Jiyoung Day
Roberts-Rapp, Riser
Russell, Jiyoung Shee
Stroop, Stephen Day
Cohen, Maurice
Colpitts, Tracy El
Friedman, Paula N
Gordon, The Julian
Edward, Granados
Hotisu, Stephen Sea
Class, michael are
Kratokville, Jiyoung Day
Roberts-Rapp, Riser
Russell, Jiyoung Shee
Stroop, Stephen Day
Application Number:
JP2000519086A
Publication Date:
November 13, 2001
Filing Date:
October 19, 1998
Export Citation:
Assignee:
ABBOTT LABORATORIES
International Classes:
G01N33/53; A61K38/00; A61K39/395; A61P15/00; A61P35/00; C07K14/47; C07K16/30; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/09; C12P21/02; C12Q1/68; G01N33/574; G01N33/577; (IPC1-7): C12N15/09; A61K38/00; A61K39/395; A61P15/00; A61P35/00; C07K14/47; C07K16/30; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12P21/02; C12Q1/68; G01N33/53; G01N33/574; G01N33/577
Attorney, Agent or Firm:
Yoshio Kawaguchi (3 outside)