Title:
【発明の名称】胃腸管の疾患の検出に有用な試薬および方法
Document Type and Number:
Japanese Patent JP2001522238
Kind Code:
A
Abstract:
A set of contiguous and partially overlapping cDNA sequences and polypeptides encoded thereby, designated as CS198 and transcribed from GI tract tissue, is described. These sequences are useful for detecting, diagnosing, staging, monitoring, prognosticating, preventing or treating, or determining the predisposition of an individual to diseases and conditions of the GI tract, such as GI tract cancer. Also provided are antibodies which specifically bind to CS198-encoded polypeptide or protein, and agonists or inhibitors which prevent action of the tissue-specific CS198 polypeptide, which molecules are useful for the therapeutic treatment of GI tract diseases, tumors or metastases.
Inventors:
Billings-Medal, Patricia A
Cohen, Maurice
Colpitts, Tracy El
Friedman, Paula N
Gordon, The Julian
Edward N, Granados
Haydn Mark
Hotsujisu, Stephen Shii
Class, michael earl
Kratokville, Jiyoung Day
Roberts-Lapp, Lisa
Russell, Jiyoung Shii
Stroop, Stephen Day
Cohen, Maurice
Colpitts, Tracy El
Friedman, Paula N
Gordon, The Julian
Edward N, Granados
Haydn Mark
Hotsujisu, Stephen Shii
Class, michael earl
Kratokville, Jiyoung Day
Roberts-Lapp, Lisa
Russell, Jiyoung Shii
Stroop, Stephen Day
Application Number:
JP54190998A
Publication Date:
November 13, 2001
Filing Date:
March 30, 1998
Export Citation:
Assignee:
Abbot Laboratories
International Classes:
G01N33/53; C07K14/47; C07K16/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/09; C12P21/02; C12Q1/68; (IPC1-7): C12Q1/68; C07K14/47; C07K16/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/09; C12P21/02; G01N33/53
Attorney, Agent or Firm:
Yoshio Kawaguchi (2 outside)