Title:
【発明の名称】天然ヌクレオシドおよびその改変類縁体を産生するための組換え細菌株
Document Type and Number:
Japanese Patent JP2002533126
Kind Code:
A
Abstract:
Novel strains of genetically modified prokaryotic micro-organisms capable of expressing polypeptides having the enzyme activity of the enzymes uridine phosphorylase (UdP) and purine nucleoside phosphorylase (PNP) are described; the strains in question can be used, both in the form of whole cells and in the form of crude or purified extracts, to catalyse transglycosylation reactions between a donor nucleoside and an acceptor base with particularly high yields. The associated plasmid vectors are also described.
Inventors:
Giuseppe bestess
Simona Cali
Daniella Gisotti
Gaetano Orsini
Giancarlo Tonon
Gabriele Tsuffi
Simona Cali
Daniella Gisotti
Gaetano Orsini
Giancarlo Tonon
Gabriele Tsuffi
Application Number:
JP2000591198A
Publication Date:
October 08, 2002
Filing Date:
December 23, 1999
Export Citation:
Assignee:
Norpharma SP
International Classes:
C12N1/21; C12N9/10; C12N15/54; C12P19/02; C12P19/38; C12P19/40; C12N15/09; (IPC1-7): C12N15/09; C12N1/21; C12N9/10
Domestic Patent References:
| JPH06253854A | 1994-09-13 | |||
| JPS5495794A | 1979-07-28 | |||
| JPS56164793A | 1981-12-17 | |||
| JPH02308797A | 1990-12-21 | |||
| JPH10286097A | 1998-10-27 | |||
| JPH10201481A | 1998-08-04 |
Foreign References:
| WO1998029432A1 | 1998-07-09 |
Attorney, Agent or Firm:
Yoshikazu Tani (2 outside)