Title:
【発明の名称】標的分子の活性部位またはクレフトと特異的に相互作用する認識分子
Document Type and Number:
Japanese Patent JP2000515002
Kind Code:
A
Abstract:
The invention relates to a recognition molecule, being capable of interacting with an active site or cleft of a target molecule, which recognition molecule comprises an exposed loop structure, which extends from a basic recognition unit. The loop structure is for example the CDR3 of a camelid species heavy chain antibody having a binding specificity fo the active site or cleft of a target molecule, or a derived version of such a CDR3. The basic recognition unit is for example formed by an antibody-type structure having binding affinity for the target molecule.
Inventors:
Mui der Mans, Serge
Wins, rohde
Wins, rohde
Application Number:
JP53565097A
Publication Date:
November 14, 2000
Filing Date:
June 27, 1997
Export Citation:
Assignee:
Frahms Inn Uniferzier Institute Institute Fall Biotechnology Wesette Way
International Classes:
G01N33/531; A61K39/00; A61K39/395; A61K45/00; A61P39/02; A61P43/00; C07K16/00; C07K16/12; C07K16/18; C07K16/40; C12N15/09; C12N15/10; C12N15/62; C12P21/02; G01N33/50; A61K38/00; C12R1/19; (IPC1-7): C12N15/09; A61K39/00; A61K39/395; A61K45/00; A61P39/02; A61P43/00; C07K16/00; C07K16/40; C12P21/02; G01N33/531
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)