Title:
尿ゲルゾリンの検出および定量化
Document Type and Number:
Japanese Patent JP2010536043
Kind Code:
A
Abstract:
The invention relates generally to gelsolin binding agents (e.g., antibodies) which can bind to gelsolin polypeptides. Gelsolin binding agents of the invention are useful, alone or in combination, to detect a gelsolin polypeptide (a.k.a., the target polypeptide) in a test sample as well as to purify native gelsolin proteins. Gelsolin binding agents are also useful to diagnose, a gelsolin related medical condition in subjects in need thereof. Kits to detect gelsolin in biological samples are provided by the present invention.
Inventors:
Shen En Yun
Yuzen
Elephant min
Guo Fei
Yuzen
Elephant min
Guo Fei
Application Number:
JP2010520409A
Publication Date:
November 25, 2010
Filing Date:
August 15, 2008
Export Citation:
Assignee:
Mountgate Group Limited
International Classes:
G01N33/53; C07K14/47; C07K16/18; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/09; C12P21/08
Domestic Patent References:
| JP2009530612A | 2009-08-27 |
Other References:
JPN6012056578; Ｂｉｏｃｈｅｍ．Ｊ． Ｖｏｌ．３８５, 2005, ｐ．６５９-６６５
JPN6012056579; Ｔｈｅ Ｊｏｕｒｎａｌ ｏｆ Ｃｅｌｌ Ｂｉｏｌｏｇｙ Ｖｏｌ．１０２, 1986, ｐ．２２７-２３６
JPN6012056580; Ｃｅｌｌ Ｍｏｔｉｌｉｔｙ ａｎｄ ｔｈｅ Ｃｙｔｏｓｋｅｌｅｔｏｎ Ｖｏｌ．５６, 2003, ｐ．９４-１０８
JPN6012056581; Ｃｒｉｔｉｃａｌ Ｃａｒｅ Ｍｅｄｉｃｉｎｅ Ｖｏｌ．２５, 1997, ｐ．５９４-５９８
JPN6012056579; Ｔｈｅ Ｊｏｕｒｎａｌ ｏｆ Ｃｅｌｌ Ｂｉｏｌｏｇｙ Ｖｏｌ．１０２, 1986, ｐ．２２７-２３６
JPN6012056580; Ｃｅｌｌ Ｍｏｔｉｌｉｔｙ ａｎｄ ｔｈｅ Ｃｙｔｏｓｋｅｌｅｔｏｎ Ｖｏｌ．５６, 2003, ｐ．９４-１０８
JPN6012056581; Ｃｒｉｔｉｃａｌ Ｃａｒｅ Ｍｅｄｉｃｉｎｅ Ｖｏｌ．２５, 1997, ｐ．５９４-５９８
Attorney, Agent or Firm:
Koichi Tsujii
Sadao Kumakura
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Shimura
Sadao Kumakura
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Shimura