To provide a method for evaluating uterine leiomyosarcoma by detecting mutation site of JAK1 kinase gene in a uterine smooth muscle tissue or cells.
There are provided an oligonucleotide comprising a partial sequence selected from the group consisting of a partial sequence of a JAK1 kinase gene containing at least one of mutation sites (A2), (A3), (A5) and (A6) of the JAK1 kinase gene and a partial sequence of LMP2 promoter containing at least one of mutation sites (B2) and (B4) of the LMP2 promoter, or a labeled product of the oligonucleotide; and the oligonucleotide comprising a partial sequence composed of 10-30 bases or a sequence complementary to the partial sequence, or its labeled product, including (A2) G2626A, (A3) G2642T, (A5) A2960C, (A6) A2985T, (B2) C214T and (B4) A217G.
KOBAYASHI YUKIHIRO
SANO KENJI
HORIUCHI SHOKO
KONISHI IKUO
Satoshi Fujita
Natsuo Tanaka