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Title:
統合失調症の治療のための重水素化1−ピペラジノ−3−フェニルインダン
Document Type and Number:
Japanese Patent JP2014520140
Kind Code:
A
Abstract:
The present invention relates to deuterated 1-piperazino-3-phenyl-indanes and salts thereof with activity at dopamine receptors D1 and D2 as well as the 5HT2 receptors in the central nervous system, to medicaments comprising such compounds as active ingredients, to the use of such compounds in the treatment of diseases in the central nervous system, and to methods of treatment comprising administration of such compounds.

Inventors:
Jorgensen, Moten
Anderson, Peter, a phon guard
Jansen, Clowes, gell ヴィグ
A ヴェネ guard, a helmet, a グロウ land
バドロ, ラッシーナ
Jacobsen, Mikkel, fog
Application Number:
JP2014516459A
Publication Date:
August 21, 2014
Filing Date:
June 19, 2012
Export Citation:
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Assignee:
Haar Lund Beck アクチエゼルスカ bed
International Classes:
C07D241/06; A61K31/4515; A61K31/454; A61K31/4545; A61K31/495; A61K31/496; A61K31/497; A61K31/506; A61K31/551; A61K31/5513; A61K31/554; A61K45/00; A61K47/40; A61P25/18; A61P25/24; C07C45/67; C07C45/68; C07C47/55; C07C49/697; C07B53/00; C07B57/00; C07B59/00; C07B61/00
Domestic Patent References:
JP2007502784A2007-02-15
JPH07505895A1995-06-29
Foreign References:
WO2011022682A12011-02-24
WO2011059080A12011-05-19
Other References:
JPN5009007399; FOSTER A B: ADVANCES IN DRUG RESEARCH V14, 1985, P1-40, ACADEMIC PRESS
JPN6012038150; Blake, Martin I. et al.: 'Studies with deuterated drugs' Journal of Pharmaceutical Sciences 64(3), 1975, 367-391
JPN5010005926; KUSHNER DJ: CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY V77 N2, 19990201, P79-88
Attorney, Agent or Firm:
Kobayashi 浩
Norio Omori
Yasuhito Suzuki