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Title:
アテローム性動脈硬化症の治療のためのペプチドに基づいた免疫治療、及び酸化した低密度リポ蛋白質に対する免疫応答の測定のためのペプチドベースのアッセーの開発
Document Type and Number:
Japanese Patent JP2004529143
Kind Code:
A
Abstract:
The present invention relates to fragments of apolipoprotein B, in particular defined peptides thereof, for immunization or therapeutic treatment of mammals, including humans, against ischemic cardiovascular diseases, as well as diagnosing the presence or absence of antibodies related to increased or decreased risk of developing ischemic cardiovascular diseases, using one or more of said peptides in an ELISA (Enzyme Linked Immuno Sorbent Assay).

Inventors:
Nilsson, Jean
Shah, Predman, Kay.
Application Number:
JP2002578993A
Publication Date:
September 24, 2004
Filing Date:
April 05, 2002
Export Citation:
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Assignee:
Forscar Patent Esday Arb
Cedars-Sinai Medical Center
International Classes:
G01N33/53; A61K38/00; A61K38/17; A61K39/00; A61K39/385; A61K39/39; A61K39/395; A61P9/10; C07K14/775; A61K; (IPC1-7): C07K14/775; A61K38/00; A61K39/00; A61K39/385; A61K39/39; A61K39/395; A61P9/10; G01N33/53
Domestic Patent References:
JP2000509993A2000-08-08
Foreign References:
WO1999008109A21999-02-18
Attorney, Agent or Firm:
Masaaki Ogura