Title:
コンピュータモデルを使用して治療標的を同定するための装置および方法
Document Type and Number:
Japanese Patent JP2007505405
Kind Code:
A
Abstract:
Apparatus and method for identifying therapeutic targets of a biological system in a disease state are described. In one implementation, a method uses a computer model of the biological system. The method includes identifying a set of functions of a biological constituent of the biological system. The method also includes executing the computer model in the absence of a modification of the set of functions to produce a first output and executing the computer model based on the modification of the set of functions to produce a second output. The method further includes comparing the second output with the first output to identify the biological constituent as a therapeutic target.
Inventors:
Patterson, Thomas S.
Wernberg, Reef Gustaf
Wernberg, Reef Gustaf
Application Number:
JP2006526328A
Publication Date:
March 08, 2007
Filing Date:
September 10, 2004
Export Citation:
Assignee:
Enteros Incorporated
International Classes:
G16B20/00; C12Q1/68; G01N31/00; G01N33/48; G01N33/50; G06F17/10; G16B5/10; G06F
Foreign References:
| US6108635A | 2000-08-22 | |||
| US6108635A | 2000-08-22 |
Other References:
JPN6010046009, Ｓｔｏｋｅｓ， Ｃ．Ｌ．, "Ａｓｔｈｍａ ＰｈｙｓｉｏＬａｂ： ａ ｄｙｎａｍｉｃ， ｃｏｍｐｕｔｅｒ−ｂａｓｅｄ ｍａｔｈｅｍａｔｉｃａｌ ｍｏｄｅｌ ｏｆ ａｃｕｔｅ ａｎｄ ｃｈｒｏｎｉｃ ａｓｔｈｍａ", Ｐｒｏｃｅｅｄｉｎｇｓ ｏｆ ｔｈｅ Ｆｉｒｓｔ Ｊｏｉｎｔ ＢＭＥＳ／ＥＭＢＳ Ｃｏｎｆｅｒｅｎｃｅ, 199910, ｖｏｌ．２, ｐ．１２０８
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita