Title:
糖尿病の治療または予防薬
Document Type and Number:
Japanese Patent JP5697260
Kind Code:
B2
Abstract:
A therapeutic or prophylactic agent for diabetes comprising a thiazolidine derivative as a PPAR-³ agonist as an effective component, which agent shows a reduced side effect of the PPAR-³ agonist, is disclosed. The therapeutic or prophylactic agent for diabetes comprises a particular IP agonist such as beraprost sodium (BPS), and a thiazolidine derivative such as pioglitazone or a pharmaceutically acceptable salt thereof. Since the therapeutic or prophylactic agent of the present invention shows a sufficiently effective hypoglycemic action without being accompanied by side effects characteristic to PPAR-³ agonists (e.g., body weight gain), the agent is useful as a highly safe and effective therapeutic or prophylactic agent for diabetes.
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Inventors:
Yudai Takahashi
Yuki Kumagai
Takashi Kadowaki
Naoto Kubota
Tetsuya Kubota
Yuki Kumagai
Takashi Kadowaki
Naoto Kubota
Tetsuya Kubota
Application Number:
JP2011540551A
Publication Date:
April 08, 2015
Filing Date:
November 12, 2010
Export Citation:
Assignee:
TORAY INDUSTRIES,INC.
National University Corporation Tokyo University
National University Corporation Tokyo University
International Classes:
A61K31/4439; A61K31/41; A61K31/4184; A61K31/506; A61K31/5585; A61P3/04; A61P3/10; A61P43/00
Domestic Patent References:
| JP2001512478A | 2001-08-21 | |||
| JP2007536229A | 2007-12-13 | |||
| JP2008530097A | 2008-08-07 | |||
| JPH10251146A | 1998-09-22 | |||
| JP2001512478A | 2001-08-21 | |||
| JP2007536229A | 2007-12-13 | |||
| JP2008530097A | 2008-08-07 | |||
| JPH10251146A | 1998-09-22 |
Attorney, Agent or Firm:
Eijiro Tanikawa