Title:
マイコバクテリアによる感染の診断方法およびそのための試薬
Document Type and Number:
Japanese Patent JP2012518422
Kind Code:
A
Abstract:
The present invention provides a method of specifically detecting the presence of one or more Mycobacteria of the M. tuberculosis complex, said method comprising detecting ilvC nucleic acid of one or more Mycobacteria of the M. tuberculosis complex in a sample under conditions that do not detect ilvC nucleic acid of the M. avium complex. The invention also provides methods of diagnosis and treatment of tuberculosis in a subject employing the specific detection ilvC nucleic acid of one or more Mycobacteria of the M. tuberculosis complex.
Inventors:
Lindner, Robin
Garthwaite, Ian
Garthwaite, Ian
Application Number:
JP2011551376A
Publication Date:
August 16, 2012
Filing Date:
February 26, 2010
Export Citation:
Assignee:
TYRIAN DIAGNOSTICS LIMITED
International Classes:
C12Q1/04; A61K45/00; A61P31/06; C12N15/09; C12Q1/68; G01N33/569
Foreign References:
| WO2009143565A1 | 2009-12-03 | |||
| US20040254349A1 | 2004-12-16 | |||
| WO2007034118A1 | 2007-03-29 | |||
| US20050287534A1 | 2005-12-29 |
Other References:
JPN6014026507; ＤＩＡＧＮＯＳＴＩＣ ＭＩＣＲＯＢＩＯＬＯＧＹ ＡＮＤ ＩＮＦＥＣＴＩＯＵＳ ＤＩＳＥＡＳＥ Ｖｏｌ．５４, 2006, Ｐ．２１７-２２２
JPN6014026506; 'Ｍｙｃｒｏｂａｃｔｅｒｉｕｍ ａｖｉｕｍ ａｃｅｔｏｌａｃｔａｔｅ ｓｙｎｔｈａｓｅ（ｉｌｖＢＮ） ａｎｄ ａｃｅｔｏｈｙｄｒｏｘｙ ａｃｉｄ ｉｓｏｍｅｒｏｒｅｄｕｃｔａｓｅ （ｉｌｖＣ） ｇｅｎｅ' ＥＭＢＬ-Ｂａｎｋ： Ｌ４９３９２．１ , 20050417
JPN6014026506; 'Ｍｙｃｒｏｂａｃｔｅｒｉｕｍ ａｖｉｕｍ ａｃｅｔｏｌａｃｔａｔｅ ｓｙｎｔｈａｓｅ（ｉｌｖＢＮ） ａｎｄ ａｃｅｔｏｈｙｄｒｏｘｙ ａｃｉｄ ｉｓｏｍｅｒｏｒｅｄｕｃｔａｓｅ （ｉｌｖＣ） ｇｅｎｅ' ＥＭＢＬ-Ｂａｎｋ： Ｌ４９３９２．１ , 20050417
Attorney, Agent or Firm:
Hitoshi Shinbo