Title:
神経変性疾患の診断法
Document Type and Number:
Japanese Patent JP2010517540
Kind Code:
A
Abstract:
The present invention provides a method for diagnosing a neurodegenerative disease or for determining the predisposition of a subject to a neurodegenerative disease. In particular, the methods of the present invention comprise detecting a marker linked to map position 9p21, e.g., a marker within an opioid receptor sigma 1 (OPRS1) gene or an expression produce thereof. The present invention also provides a method for identifying new markers that are associated with a neurodegenerative disease. The present invention also provides mutant forms of an OPRS1 gene or an expression product thereof and reagents for detecting those mutations.
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Inventors:
Shofield, Peter
Quoc, John
Luti, Agnes
Quoc, John
Luti, Agnes
Application Number:
JP2009548548A
Publication Date:
May 27, 2010
Filing Date:
February 08, 2008
Export Citation:
Assignee:
Poumuri Limited
International Classes:
C12N15/09; A61K45/00; A61P21/02; A61P25/00; A61P25/16; A61P25/28; C07K14/47; C07K16/18; C12Q1/68; C12P21/08
Attorney, Agent or Firm:
Hiroshi Kobayashi
Eiji Katayama
Norio Omori
Yasuhito Suzuki
Eiji Katayama
Norio Omori
Yasuhito Suzuki