Title:
DIAGNOSTIC TUMOR MARKER, DRUG SCREENING FOR TUMORIGENESIS INHIBITION, AND COMPOSITION AND METHOD FOR TREATMENT OF CANCER
Document Type and Number:
Japanese Patent JP2010106028
Kind Code:
A
Abstract:
To provide a series of compositions, methods, kits, articles and species mainly associated with the diagnosis and/or treatment of cell proliferation, specifically cancer.
The figure shows a MUC1 receptor. Cell proliferation associated with aberrant expression of MUC1 is particularly focused upon. An important aspect of mechanisms associated with MUC1 cell proliferation and tumorigenesis is clarified. In addition, a new molecular target for drug screening assay is provided. Compounds that inhibit MUC1-independent tumorigenesis are identified using this assay. Accordingly, early diagnostic assay becomes possible.
Inventors:
BAMDAD CYNTHIA C
BAMDAD R SHOSHANA
BAMDAD R SHOSHANA
Application Number:
JP2009271611A
Publication Date:
May 13, 2010
Filing Date:
November 30, 2009
Export Citation:
Assignee:
MINERVA BIOTECHNOLOGIES CORP
International Classes:
A61K38/00; A61K31/198; A61K31/336; A61K31/416; A61K31/44; A61K45/00; A61P13/08; A61P35/00; C07K14/71; C07K19/00; C12Q1/02; C12Q1/68; G01N27/447; G01N33/15; G01N33/50; G01N33/543; G01N33/574
Domestic Patent References:
| JPH02273195A | 1990-11-07 | |||
| JPH02273195A | 1990-11-07 | |||
| JP2004515472A | 2004-05-27 |
Attorney, Agent or Firm:
Shinjiro Ono
Kazuo Shamoto
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Mitsutoshi Nakamura
Kazuo Shamoto
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Mitsutoshi Nakamura
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