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Title:
CB2受容体を制御するジアゼパン化合物
Document Type and Number:
Japanese Patent JP2011500820
Kind Code:
A
Abstract:
Compounds of formula (I) are disclosed. Compounds according to the invention bind to and are agonists, antagonists or inverse agonists of the CB2 receptor, and are useful for treating inflammation. Those compounds which are agonists are additionally useful for treating pain.

Inventors:
Cirillo Pierre Francesco
Hicky Eugene Richard
Leeter Doris
Wu Li Feng
Sindel Lenny
Amousze Patricia
Herman Monica
Walker edward
Application Number:
JP2010531160A
Publication Date:
January 06, 2011
Filing Date:
October 21, 2008
Export Citation:
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Assignee:
Boehringer Ingelheim International GmbH
International Classes:
C07D243/08; A61K31/551; A61P1/00; A61P1/02; A61P1/04; A61P1/16; A61P1/18; A61P5/00; A61P5/14; A61P5/48; A61P7/00; A61P7/04; A61P7/06; A61P7/10; A61P9/00; A61P9/10; A61P11/00; A61P11/02; A61P11/04; A61P11/06; A61P11/08; A61P11/16; A61P13/02; A61P13/08; A61P13/10; A61P13/12; A61P15/00; A61P17/00; A61P17/02; A61P17/04; A61P17/06; A61P19/00; A61P19/02; A61P19/06; A61P19/08; A61P21/00; A61P21/04; A61P25/00; A61P25/06; A61P25/14; A61P25/16; A61P25/28; A61P27/02; A61P27/16; A61P29/00; A61P31/04; A61P31/08; A61P31/12; A61P31/16; A61P31/18; A61P31/22; A61P35/00; A61P35/02; A61P35/04; A61P37/00; A61P37/08; A61P43/00; C07D401/04; C07D401/14; C07D403/04; C07D403/14; C07D405/14; C07D413/04; C07D413/14; C07D417/04; C07D417/14; C07D473/32; C07D491/048; C07D495/04; C07D498/04
Domestic Patent References:
JP2006504663A2006-02-09
Foreign References:
WO2004110376A22004-12-23
WO2007056046A12007-05-18
WO2007070506A22007-06-21
WO2006106423A22006-10-12
WO2007126935A22007-11-08
Other References:
JPN7012003850; FEBS LETTERS 436, 1998, pp.449-54
JPN7012003851; PHARMACOLOGY & THERAPEUTICS 106, 2005, pp.133-45
JPN7012003848; EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 43, 2008, pp.1570-74
JPN7012003849; JOURNAL OF MEDICINAL CHEMISTRY 48(6), 2005, pp.1857-72
Attorney, Agent or Firm:
Koichi Tsujii
Sadao Kumakura
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Akizawa