Title:
ジベンゾキシアゼピン類
Document Type and Number:
Japanese Patent JP2006503869
Kind Code:
A
Abstract:
10-Alkyl-11-oxo-10,11-dihydro-dibenz-(b,f)(1,4)-azepine derivatives (I) are new. Dibenzoxazepinones of formula (I) and their salts, solvates and solvated salts are new. Y = 1-6C alkylidene, optionally (i) containing one or more double or triple bonds, (ii) substituted by one or more =O and/or (iii) having one or more C-atoms replaced by N, O or S, provided that any heteroatom in Y is not bonded directly to R3 or to another heteroatom in Y; R1, R4 = halo, CF3, OCF3, CN, NO2, NH2, alkylamino, OH, alkyl, alkoxy, COOH, alkoxycarbonyl, CONH2 or alkylaminocarbonyl; n = 0-3; m = 0-2; R2 = alkyl, optionally substituted by 1 or 2 of halo, OH, alkoxy, COOH, alkoxycarbonyl, CONH2, alkylaminocarbonyl or Q; Q = aryl, heteroaryl, cycloalkyl or heterocyclyl (all optionally substituted by 1-3 groups R1); R3 = OH or NH2. An Independent claim is included for the preparation of (I).
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Inventors:
Claudia Hirth-Dietrich
Jack Dumas
Elizabeth Voltering
Beatrix Stelte-Ludwig
Dmitry Zubov
Michael blants
Peter Ellinghouse
Dirk Heimbach
Johannes Cape Bell Ring
Karl-Heinz Schlenmer
Siegfried Zeiss
Franz Tumpe
Jack Dumas
Elizabeth Voltering
Beatrix Stelte-Ludwig
Dmitry Zubov
Michael blants
Peter Ellinghouse
Dirk Heimbach
Johannes Cape Bell Ring
Karl-Heinz Schlenmer
Siegfried Zeiss
Franz Tumpe
Application Number:
JP2004542338A
Publication Date:
February 02, 2006
Filing Date:
August 30, 2003
Export Citation:
Assignee:
Bayer HealthCare AG
International Classes:
C07D267/20; A61K31/553; A61P1/04; A61P1/16; A61P9/00; A61P9/10; A61P11/00; A61P17/06; A61P19/02; A61P19/10; A61P25/04; A61P29/00; A61P35/00; A61P37/02; A61P37/06; A61P43/00; C07D413/06
Attorney, Agent or Firm:
Aoyama Aoi
Mitsutaka Iwasaki
Shoji Nakajima
Kazuaki Kojima
Yasuo Shibata
Mitsutaka Iwasaki
Shoji Nakajima
Kazuaki Kojima
Yasuo Shibata