DIELS-ALDER ADDUCT FROM STREPTAZOLINE AND NAPHTHOQUINONE ANDITS OXIDATION PRODUCT

Title:

DIELS-ALDER ADDUCT FROM STREPTAZOLINE AND NAPHTHOQUINONE ANDITS OXIDATION PRODUCT

Document Type and Number:

Japanese Patent JPS62273984

Kind Code:

A

Abstract:

Streptazoline is reacted with naphthoquinones in a Diels-Alder reaction, and the adduct is then oxidized. The resulting compounds have cytotoxic activity, in particular against leukemia cells, and have an antimicrobial action and act against protozoa.

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Inventors:

HANSU URURIHI HOTSUPE
ZUZANNE GURAAPURAI
HARUTOMUUTO FUERUSUKOU
MERUTEN SHIYURINGUMAN
HANSU PEETAA KUREEMAA
MATEIIASU BUIISUNAA
YOOAHIMU TEIIMU

Application Number:

JP11491187A

Publication Date:

November 28, 1987

Filing Date:

May 13, 1987

Export Citation:

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Assignee:

HOECHST AG

International Classes:

A61K31/42; A61K31/47; A61P31/04; A61P33/02; A61P35/02; C07D498/06; C07F7/18; C07H15/252; C07H17/00; (IPC1-7): A61K31/47; C07D221/00; C07D263/00; C07D498/06; C07F7/18

Attorney, Agent or Firm:

Chika Takagi

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