Title:
ジヒドロベンゾジアゼピンおよび異脂肪血症におけるそれらの使用
Document Type and Number:
Japanese Patent JP4699663
Kind Code:
B2
Abstract:
The invention concerns a benzodiazepin derivative of formula (I) and their use for treating dyslipidemia, atherosclerosis, diabetes and its complications.
Inventors:
Bertheron, Jean-Jarke
Guerrier, Daniel
Brunet, Michelle
Zeye, Jean-Jarke
Contal, Francis
Osei, Frederik
Guerrier, Daniel
Brunet, Michelle
Zeye, Jean-Jarke
Contal, Francis
Osei, Frederik
Application Number:
JP2001507812A
Publication Date:
June 15, 2011
Filing Date:
July 04, 2000
Export Citation:
Assignee:
Merck Patent Gesellschaft mit beschraenkter Haftung
International Classes:
C07D513/04; A61K31/538; A61K31/55; A61K31/551; A61K31/5517; A61P3/00; A61P3/06; A61P3/10; A61P9/00; A61P9/10; C07D243/04; C07D401/12; C07D405/12; C07D409/12; C07D413/12; C07D487/04; C07D495/14; C07D513/14
Domestic Patent References:
| JP59155373A | ||||
| JP9087260A | ||||
| JP8157369A |
Foreign References:
| US3780023 |
Other References:
Linda L. Setescak et al.,(±)-4-Aryl-4,5-dihydro-3H-1,3-benzodiazepines. 3. 2-Phenyl and 2-Amino Analogues as Potential Antihypertensive Agents,Journal of Medicinal Chemistry,1984年,Vol.27, No.3,p.401-404
Timothy Jen et al.,Amidines. 4. Synthesis of Tricyclic Guanidines Related to 1,2,3,5-Tetrahydroimidazo[2,1-b]quinazoline, a New Antihypertensive Agent,Journal of Medicinal Chemistry,1973年,Vol.16, No.4,p.407-411
Timothy Jen et al.,Amidines. 4. Synthesis of Tricyclic Guanidines Related to 1,2,3,5-Tetrahydroimidazo[2,1-b]quinazoline, a New Antihypertensive Agent,Journal of Medicinal Chemistry,1973年,Vol.16, No.4,p.407-411
Attorney, Agent or Firm:
Akio Miyazaki
Katsuhiro Ito
Ishibashi Masayuki
Katsuhiro Ito
Ishibashi Masayuki