Title:
HNEインヒビターとしてのジヒドロピリジノン誘導体
Document Type and Number:
Japanese Patent JP4619122
Kind Code:
B2
Abstract:
The invention relates to novel dihydropyridinone derivatives, processes for their preparation, and their use in medicaments, especially for the treatment of chronic obstructive pulmonary diseases, acute coronary syndrome, acute myocardial infarction and heart failure development.
Inventors:
Heike Gillen-Hertwig
Volkhard Min-Jean Li
Ulrich Rosent Letter
Karl-Heinz Schlenmer
Sven Aller Heiligen
Lyra Terran
Lars Belfucker
Jörg Kerdenig
Mary F. Fitzgerald
Kevin Nash
Barbara Albrecht
Dirk Moyler
Volkhard Min-Jean Li
Ulrich Rosent Letter
Karl-Heinz Schlenmer
Sven Aller Heiligen
Lyra Terran
Lars Belfucker
Jörg Kerdenig
Mary F. Fitzgerald
Kevin Nash
Barbara Albrecht
Dirk Moyler
Application Number:
JP2004532090A
Publication Date:
January 26, 2011
Filing Date:
August 18, 2003
Export Citation:
Assignee:
Bayer Schering Pharma Aktiengesellschaft
International Classes:
C07D211/90; A61K31/4418; A61K31/443; A61K31/4439; A61K31/444; A61K31/4545; A61K31/496; A61K31/5377; A61K31/695; A61P1/00; A61P1/02; A61P1/04; A61P1/16; A61P1/18; A61P9/00; A61P9/04; A61P9/10; A61P9/12; A61P9/14; A61P11/00; A61P11/02; A61P11/08; A61P11/16; A61P13/12; A61P17/00; A61P17/06; A61P19/02; A61P25/00; A61P27/16; A61P29/00; A61P31/00; A61P31/04; A61P31/10; A61P31/12; A61P35/00; A61P37/00; A61P37/08; A61P43/00; C07D211/86; C07D401/04; C07D405/04; C07D417/06; C07F7/18
Other References:
OSMAN,A.I. et al,Synthesis of functionally substituted pyridine and thiophene derivatives,Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry,1998年,Vol.37B, No.4,p.399-403
Attorney, Agent or Firm:
Mitsuo Tanaka
Takuji Yamada
Mitsutaka Iwasaki
Aoyama Aoi
Yasuo Shibata
Takuji Yamada
Mitsutaka Iwasaki
Aoyama Aoi
Yasuo Shibata