Title:
ジヒドロキシフェニルアラニン誘導体
Document Type and Number:
Japanese Patent JP2008540465
Kind Code:
A
Abstract:
The invention relates to derivatives of dihydroxyphenylalanine, to their synthesis and to pharmaceutical compositions containing said derivatives of dihydroxyphenylalanine. Furthermore, the invention relates to the use of said derivatives of dihydroxyphenylalanine and said pharmaceutical compositions for the treatment and prophylaxis of movement disorders, neurodegenerative diseases, Alzheimer's disease, Parkinson's disease, hemiparkinson-hemiatrophy, parkinsonian syndrome, Lewy body disease, frontotemporal dementia, Lytico-Bodig disease (parkinsonism/dementia/amyotrophic lateral sclerosis), striatonigral degeneration, Shy-Drager syndrome, sporadic olivopontocerebellar degeneration, progressive atrophy of the globus pallidus, progressive supranuclear palsy, Hallervorden-Spatz disease, Huntington's disease, X-linked dystonia-parkinsonism (Lubag), mitochondrial cytopathy with striatal necrosis, neuroacanthocytosis, restless legs syndrome, Wilson's disease.
Inventors:
Shiro, Gizela
Application Number:
JP2008510404A
Publication Date:
November 20, 2008
Filing Date:
May 14, 2006
Export Citation:
Assignee:
El Neu Rocks Limited
International Classes:
C07C233/49; A61K31/198; A61K31/216; A61K31/381; A61K31/4738; A61K31/48; A61P9/10; A61P25/00; A61P25/08; A61P25/14; A61P25/16; A61P25/28; A61P43/00; C07C235/44; C07D339/04; C07D409/12
Domestic Patent References:
| JPH0296556A | 1990-04-09 |
Foreign References:
| US4035507A | 1977-07-12 | |||
| US3891696A | 1975-06-24 |
Attorney, Agent or Firm:
Hiromichi Nanjo