Title:
液体システムにおける作動流体の希釈減少法
Document Type and Number:
Japanese Patent JP4494877
Kind Code:
B2
Abstract:
A method of transporting a desired fluid in a channel includes: providing a working fluid to transport the desired fluid, such as a sample; providing a first segment of a first buffer fluid which is immiscible with the working fluid and the desired fluid; providing a first segment of the desired fluid; providing a second segment of a second buffer fluid which is immiscible with the working fluid and the desired fluid; providing the desired fluid to be transported and further manipulated; and transporting the desired fluid in the channel by applying a motive force to the working fluid which in turn exerts force against the desired fluid through the first and second buffer fluid. The method prevents dilution of a sample in an apparatus such as a diagnostic analyzer or an apparatus for immunohematological testing of blood. A microfluidics handling system includes a microsystem platform that has: a substrate having: a first flat, planar surface; and a second flat planar surface opposite to the first surface. The first surface includes: at least one microchannel; an optional reagent source; an optional reaction chamber; a source of motive force to transport the fluid; a working fluid in the microchannels; a first segment of a first buffer fluid which is immiscible with the working fluid and the desired fluid; a first segment of the desired fluid; a second segment of a second buffer fluid which is immiscible with the working fluid and the desired fluid; and the desired fluid to be transported and further manipulated, wherein the fluid is present in the microchannels in the order of working fluid; first buffer fluid; first segment of the desired fluid, second buffer fluid; and the desired fluid.
Inventors:
Merit Jacobs
Son Din
Son Din
Application Number:
JP2004181332A
Publication Date:
June 30, 2010
Filing Date:
June 18, 2004
Export Citation:
Assignee:
Ortho-Clinical Diagnostics, Incorporated
International Classes:
G01N35/08; F04B19/00; G01N35/00; G01N37/00
Domestic Patent References:
| JP7159415A | ||||
| JP10123152A | ||||
| JP7055817A | ||||
| JP4161856A | ||||
| JP2005503572A |
Foreign References:
| WO2003026798A1 |
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Tetsuji Koga
Masatoshi Iwade
Masaya Nishiyama
Takashi Ishida
Tetsuji Koga
Masatoshi Iwade
Masaya Nishiyama