Title:
TREATING BASAL CELL-LIKE GENOTYPE CANCERS
Document Type and Number:
Japanese Patent JP2017132807
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide methods of treating a subject with cancer comprising administering a death receptor agonist to the subject.SOLUTION: Also provided herein are methods of screening a breast cancer cell for responsiveness to a DR5 agonist. Further provided herein are antibodies that selectively bind an N-terminal CARD of DDX3, a DDX3 lacking an N-terminal CARD, and an 80 kDa baculovirus IAP repeat (BIR). The methods comprise detecting in the breast cancer cell IAP proteins including an 80 kDa baculovirus IAP repeat.SELECTED DRAWING: None
Inventors:
DONALD J BUCHSBAUM
ZHOU TONG
ALBERT F LOBUGLIO
ZHOU TONG
ALBERT F LOBUGLIO
Application Number:
JP2017091303A
Publication Date:
August 03, 2017
Filing Date:
May 01, 2017
Export Citation:
Assignee:
UAB RES FOUND
International Classes:
A61K45/00; A61K31/282; A61K31/337; A61K31/704; A61K33/28; A61K39/395; A61P35/00; A61P43/00; C07K16/08; C07K16/40; G01N33/574
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
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