Title:
ホスホジエステラーゼ10阻害剤としての二置換フェニル化合物
Document Type and Number:
Japanese Patent JP2011526294
Kind Code:
A
Abstract:
Di-substituted phenyl compounds which are inhibitors of phosphodiesterase 10 are described as are processes, pharmaceutical compositions, pharmaceutical preparations and pharmaceutical use of the compounds in the treatment of mammals, including human(s) for central nervous system (CNS) disorders and other disorders which may affect CNS function. The disclosure also relates to methods for treating neurological, neurodegenerative and psychiatric disorders including but not limited to those comprising cognitive deficits or schizophrenic symptoms.
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Inventors:
Chessworth richard
Shapiro Gideon
Lipka Amy
Shapiro Gideon
Lipka Amy
Application Number:
JP2011516646A
Publication Date:
October 06, 2011
Filing Date:
June 25, 2009
Export Citation:
Assignee:
Envivo Pharmaceuticals, Inc.
International Classes:
C07D215/22; A61K31/4439; A61K31/444; A61K31/4709; A61K31/496; A61K31/498; A61K31/517; A61K31/5377; A61P1/14; A61P3/00; A61P3/04; A61P3/10; A61P15/00; A61P25/00; A61P25/14; A61P25/18; A61P25/20; A61P25/24; C07D235/14; C07D263/58; C07D401/12; C07D403/12; C07D405/12; C07D413/12; C07D417/12; C07D487/04
Foreign References:
| WO2008033455A2 | 2008-03-20 | |||
| EP1541149A1 | 2005-06-15 | |||
| WO2007129183A2 | 2007-11-15 | |||
| WO1991019697A1 | 1991-12-26 | |||
| WO1991019697A1 | 1991-12-26 |
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto