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Title:
DNA ONCOGEN CODING ONCOSTATIN-A OR ITS PART
Document Type and Number:
Japanese Patent JPH0242985
Kind Code:
A
Abstract:

PURPOSE: To produce a polypeptide that inhibits the proliferation of mammalian neoplasm cells (for example, tumor) by using a DNA coding for a special amino acid sequence through genetic engineering technique.

CONSTITUTION: A DNA fragment of about 5 or less kb, coding a peptide comprising at least 8 amino acids in the amino acid sequence represented by the formula is used to produce the objective polypeptide according to the genetic engineering.


Inventors:
TOWAADOJIKU DANIERU AARU
TODARO JIYOOJI JIEI
Application Number:
JP18382289A
Publication Date:
February 13, 1990
Filing Date:
July 18, 1989
Export Citation:
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Assignee:
ONCOGEN
International Classes:
A61K35/14; A61K35/74; G01N33/50; A61K38/00; A61K38/16; A61K39/00; A61K39/395; A61P35/00; C07H1/00; C07H21/04; C07K1/20; C07K7/02; C07K14/00; C07K14/47; C07K14/52; C07K14/745; C07K16/00; C07K16/18; C07K19/00; C12N15/02; C12N15/09; C12P21/02; C12P21/08; G01N33/53; G01N33/577; C12R1/19; C12R1/91; (IPC1-7): C12N15/12; C12P21/02
Other References:
J.BIOL.CHEM=1977
Attorney, Agent or Firm:
Aoki Akira (4 outside)