Title:
DOPAMINE-BETA-HYDROXYLASE INHIBITOR
Document Type and Number:
Japanese Patent JPS63255268
Kind Code:
A
Abstract:
Compounds of formula (I) : in which X is H, F, Cl, Br, I, C1-4alkyl, CN, NO2, SO2NH2, COOH, CHO, C1-4alkoxy, CH2OH, CF3, SO2CH3, SO2CF3 or CO2CaH2a+1 wherein a is 1-5; n is 0-5; R is hydrogen or C1-4alkyl, and R<1> is OH or NHC1-4alkylNH2; and pharmaceutically acceptable salts or hydrates thereof, processes for their preparation, intermediates useful in their preparation, pharmaceutical compositions containing them and their use in therapy as dopamine- beta -hydroxylase inhibitors.
Inventors:
JIYOSEFU ARAN FUINKERUSUTAIN
ROURENSU AIBAN KURUSU
TOOMASU BURENTO REONARUDO
ROURENSU AIBAN KURUSU
TOOMASU BURENTO REONARUDO
Application Number:
JP7085088A
Publication Date:
October 21, 1988
Filing Date:
March 24, 1988
Export Citation:
Assignee:
SMITHKLINE BECKMAN CORP
International Classes:
A61K31/415; A61P9/12; A61P43/00; C07C67/00; C07C231/00; C07C233/47; C07C253/00; C07C255/60; C07C301/00; C07C311/37; C07C313/00; C07C317/32; C07D233/84; C07D233/90; (IPC1-7): A61K31/415; C07C103/46; C07C121/78; C07C143/80; C07C147/12; C07D233/90
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)