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Title:
Drug Carriers for Tumor-Specific Targeted Administration and Their Applications
Document Type and Number:
Japanese Patent JP6294510
Kind Code:
B2
Abstract:
The present disclosure relates to a tumor-targeted drug delivery system, comprising a tumor-targeted drug carrier and a tumor-treating drug, wherein the tumor-targeted drug carrier comprises full heavy-chain human ferritin. The present disclosure also relates to a method for preparing the tumor-targeted drug delivery system comprising: depolymerizing a polymerized full heavy-chain human ferritin; adding a tumor-treating drug to the depolymerized full heavy-chain human ferritin so as to bind the tumor-treating drug to the depolymerized full heavy-chain human ferritin; and re-polymerizing the depolymerized full heavy-chain human ferritin bound with the tumor-treating drug to form a nanoparticle.

Inventors:
Yan Seok-ho
Fan Katsu Long
Liang
King Fei
Dan virtue people
Zhang Virtue Shi
Fine quiet
Yang East Rei
Application Number:
JP2016569947A
Publication Date:
March 14, 2018
Filing Date:
September 24, 2014
Export Citation:
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Assignee:
Institute of Biophysics, Chinese Academy of Sciences
International Classes:
A61K47/64; A61K9/14; A61K9/51; A61K47/69; A61P35/00
Domestic Patent References:
JP2011510909A
Other References:
Microbiology China,2014年 3月,Vol.41,No.3,p.520-538
Attorney, Agent or Firm:
Yasuhiko Murayama
Shinya Mitsuhiro
Tatsuhiko Abe