Title:
細胞への薬剤導入装置
Document Type and Number:
Japanese Patent JP5115686
Kind Code:
B2
Abstract:
To provide a method for introducing a medicine to cells, which introduces a foreign molecule to a large number of cells by a single application in high efficiency and an apparatus for introducing a medicine to cells.
The method for introducing a medicine to cells comprises chemically modifying a medicine with a positive charge-having substance which has an interaction with the medicine to form a complex with the medicine, accumulating the chemically modified substance in the vicinity of cells, irradiating a light absorption body arranged in the vicinity of the cells with a laser beam and applying an induced stress wave to the cells.
COPYRIGHT: (C)2008,JPO&INPIT
Inventors:
Minoru Ohara
Mitsuhiro Terakawa
Risa Otsuka
Shunichi Sato
Taiji Sato
Kunio Takishima
Yasuhiro Watanabe
Endo Shogo
Mizuno Katsushige
Yasunari Isada
Hiroshi Naeshiro
Satoshi Oikawa
Mitsuhiro Terakawa
Risa Otsuka
Shunichi Sato
Taiji Sato
Kunio Takishima
Yasuhiro Watanabe
Endo Shogo
Mizuno Katsushige
Yasunari Isada
Hiroshi Naeshiro
Satoshi Oikawa
Application Number:
JP2006113384A
Publication Date:
January 09, 2013
Filing Date:
April 17, 2006
Export Citation:
Assignee:
Keio University
International Classes:
A61K47/48; A61K9/127; A61K31/7105; A61K31/711; A61K38/00; A61K41/00; A61K47/24; A61K47/30; A61K47/34; A61K48/00; A61M25/00; A61M31/00; A61P43/00; C12N13/00
Domestic Patent References:
| JP2002272460A | ||||
| JP2004532205A | ||||
| JP2004537501A |
Other References:
第28回日本分子生物学会年会 講演要旨集,2005年11月25日,page 753,3P-1132
Journal of Biomedical Optics,2005年,Vol.10,No.6,pages 060501-1 ~ 060501-3
日本薬学会第126年会 要旨集,2006年 3月 6日,page 138,P30[S]am-571
Journal of Pharmacological Sciences,2006年 2月20日,Vol.100 Suppl.I 2006,page 88,O1H5-1
Optics Letters,2004年,29,11,1227-1229
Journal of Biomedical Optics,2005年,Vol.10,No.6,pages 060501-1 ~ 060501-3
日本薬学会第126年会 要旨集,2006年 3月 6日,page 138,P30[S]am-571
Journal of Pharmacological Sciences,2006年 2月20日,Vol.100 Suppl.I 2006,page 88,O1H5-1
Optics Letters,2004年,29,11,1227-1229
Attorney, Agent or Firm:
Yusuke Hiraki
Ishii Teiji
Satoshi Fujita
Natsuo Tanaka
Ishii Teiji
Satoshi Fujita
Natsuo Tanaka