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Title:
DRUG WHICH INHIBITS PRODUCTION OF PEPTIDE CONSISTING OF SPECIFIC AMINO ACID SEQUENCE
Document Type and Number:
Japanese Patent JP2015137267
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide a novel melanogenesis inhibitor by a drug which inhibits the production of αMSH (1-8) which is a peptide consisting of eight amino acids constituted in the order of the sequence of serine, tyrosine, serine, methionine, glutamic acid, histidine, phenylalanine, and arginine produced inside of the body by receiving ultraviolet rays and stress, and also to provide cosmetic compositions, pharmaceutical compositions, and food and drink compositions containing the drug inhibiting the production of the αMSH (1-8).SOLUTION: The invention provides a novel melanogenesis inhibitor which inhibits the production of a peptide consisting of eight amino acids constituted in the order of the sequence of serine, tyrosine, serine, methionine, glutamic acid, histidine, phenylalanine, and arginine, and cosmetic compositions, pharmaceutical compositions, food and drink compositions, particularly aiming at the prevention and improvement of skin whitening and spots/freckles, containing it.

Inventors:
TANAKA KIYOTAKA
YAMAMOTO HIROYUKI
IGUCHI KAZUAKI
Application Number:
JP2014010906A
Publication Date:
July 30, 2015
Filing Date:
January 24, 2014
Export Citation:
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Assignee:
ICHIMARU PHARCOS INC
International Classes:
A61K8/97; A23C11/10; A23L1/30; A23L2/38; A23L2/52; A61K36/18; A61K45/00; A61P17/00; A61Q1/02; A61Q1/14; A61Q19/00; A61Q19/10
Domestic Patent References:
JP2005002057A2005-01-06
JP2009108015A2009-05-21
Other References:
山本博之 他: "トリプターゼによるPOMCの活性化とメラニン産生に対する作用", 日本薬学会年会要旨集(CD−ROM), vol. 133rd, JPN6017036961, 2013, JP, pages 28amC-062