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Title:
DRUG
Document Type and Number:
Japanese Patent JPH02180822
Kind Code:
A
Abstract:
PURPOSE: To obtain a medicament containing a specific lactam derivative as an active ingredient and useful for the treatment of depression. CONSTITUTION: This medicament contains a compound of formula I [Im is an imidazolyl group of formula II or III (one of R<2> to R<4> is H, a 1-6C alkyl, a 3-6C alkenyl, phenyl, etc.; and the others are each H, a 1-6C alkyl); R<1> is H, a 1-6C alkyl, a 3-6C alkenyl, a 3-10C alkenyl, phenyl, etc.; (n) is 2, 3] or its salt or its solvate as an active ingredient, and other conventional additives, and is obtained by a conventional preparation method. The active ingredient is administered at a dose of 0.001-100mg/unit/70kg of a body weight once to four times a day. The compound of formula I includes 2,3,4,5- tetrahydro-5-(phenylmethyl)-2-[(5-methyl-1H-imidazol-4-yl)methyl]-1H-p yrido[4,3- b]indol-1-one.

Inventors:
IAN HARORUDO KOOTSU
AREKUSANDAA UIRIAMU OTSUKUSUFU
PIITAA CHIYAARUZU NOOSU
MAIKURU BURAIAN TAIAASU
Application Number:
JP22637989A
Publication Date:
July 13, 1990
Filing Date:
August 31, 1989
Export Citation:
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Assignee:
GLAXO GROUP LTD
International Classes:
A61K31/00; A61K31/435; A61K31/445; A61K31/55; C07D487/04; A61P1/04; A61P1/08; A61P25/00; A61P25/04; A61P25/18; A61P25/20; A61P25/24; A61P25/26; A61P25/28; A61P43/00; C07D471/04; (IPC1-7): A61K31/435; A61K31/55; C07D471/04; C07D487/04
Attorney, Agent or Firm:
Kazuo Sato (2 outside)



 
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