Title:
乾式造粒物及び該乾式造粒物を含有する固形製剤並びにそれらの製造方法
Document Type and Number:
Japanese Patent JP7194951
Kind Code:
B2
Abstract:
According to the present invention, a solid preparation (e.g., a chewable tablet, an orally disintegrating tablet, etc.), which comprises a drug, in particular, a hygroscopic drug, more specifically, a crude drug extract and/or a Chinese herbal drug extract, can be manufactured, without any problems in manufacturing, by using a dry-granulated material comprising (A) a drug, (B) a silicic acid compound and (C) a dicarboxylic acid higher alcohol monoester or a salt thereof. Also provided is a method for manufacturing a solid preparation which comprises a step for compression molding a dry-granulated material, said dry-granulated material comprising (A) a drug, (B) a silicic acid compound and (C) a dicarboxylic acid higher alcohol monoester or a salt thereof, or a mixture of the dry-granulated material with other component(s) (e.g., additive(s), etc.).
Inventors:
Takao Shimatani
Hiroko Ito
Hidemasa Nagai
Myo Yuki
Hiroko Ito
Hidemasa Nagai
Myo Yuki
Application Number:
JP2021128591A
Publication Date:
December 23, 2022
Filing Date:
August 04, 2021
Export Citation:
Assignee:
Teika Pharmaceutical Co., Ltd.
Toyama Prefecture
Toyama Prefecture
International Classes:
A61K36/484; A61K9/20; A61K36/076; A61K36/23; A61K36/232; A61K36/233; A61K36/258; A61K36/284; A61K36/29; A61K36/482; A61K36/65; A61K36/725; A61K36/74; A61K36/752; A61K36/884; A61K36/9068; A61K47/04; A61K47/14; A61K47/26; A61K47/32; A61K47/38
Domestic Patent References:
| JP2013136526A | ||||
| JP2014214125A | ||||
| JP2007161706A | ||||
| JP2010070576A | ||||
| JP2012001474A | ||||
| JP2000044463A | ||||
| JP2003113099A |
Other References:
岡田 尚,JRS Pharmaの口腔内速崩壊錠(ODT)用添加剤,PHARM TECH JAPAN,2015年02月05日,第31巻, 第4号(臨時増刊号),p.721-723,すべてがわかる口腔内崩壊錠ハンドブック―添加剤編―
桐生 賢,国内生産品フマル酸ステアリルナトリウム,PHARM TECH JAPAN,2015年02月05日,第31巻, 第4号(臨時増刊号),p.791-794,すべてがわかる口腔内崩壊錠ハンドブック―添加剤編―
泉 義雄,総説:漢方方剤の最新知見(11),薬理と臨床,2009年01月,第19巻, 第1号,p.69-78
桐生 賢,国内生産品フマル酸ステアリルナトリウム,PHARM TECH JAPAN,2015年02月05日,第31巻, 第4号(臨時増刊号),p.791-794,すべてがわかる口腔内崩壊錠ハンドブック―添加剤編―
泉 義雄,総説:漢方方剤の最新知見(11),薬理と臨床,2009年01月,第19巻, 第1号,p.69-78
Attorney, Agent or Firm:
Ryu Iwatani
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