To provide an improved dry powder inhaler which can disperse more uniform doses.

The dry powder inhalers with integrated active energy patient assist dispersal systems are configured with control systems which provide adjustable energy output responsive to the user's inspiratory capabilities and/or the flowability of the dry powder being administered. The multi-dose dry drug package is composed of a piezoelectric polymer substrate which flexes to deform and provide mechanical oscillation in a selected region of the package corresponding to the dry powder drug which is dispersed during inhalation by a user. Control system employs fuzzy logic to relate in response to a user's inspiratory effort.